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3689 : Inactivation of p53 in mammary luminal cells leads to their clonal expansion and facilitates development of mammary tumors with loss of luminal identity

Researchers

Presenter

  • Luwei Tao

Principal Investigators

  • Ying Xie

  • Zhe Li

Medical Centers

  • Brigham & Women's Hospital, Boston, MA

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Breast cancer

  • Solid malignancies

Biomarkers

  • C-C Motif Chemokine Ligand 28

  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

  • Keratin 8

  • Tumor protein p53

Drug/Treatment

  • Tamoxifen

  • TP53

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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