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3576 : Broad analysis of recurrent somatic mutations in cancer reveals a common novel non-coding mutation in the promoter of PMS2 associated with greatly increased tumor mutation load

Researchers

Presenter

  • Zachary R. Chalmers

Principal Investigators

  • Franklin W. Huang

  • Laurie M. Gay

  • Siraj M. Ali

  • Roman Yelensky

  • Juliann Chmielecki

  • Jeffery S. Ross

  • Vincent A. Miller

  • Philip J. Stephens

  • Levi A. Garraway

  • Garrett M. Frampton

Medical Centers

  • Foundation Medicine, Inc, Cambridge, MA

  • Dana-Farber Cancer Institute, Boston, MA

Locations

  • United States

Companies

  • Foundation Medicine,

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Solid malignancies

Biomarkers

  • Mismatch repair endonuclease PMS2

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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