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3528 : Induction of cytoprotective autophagy and senescence in response to chemotherapy and ionizing-radiation as possible mechanisms of tumor dormancy

Researchers

Presenter

  • Theresa Thekkudan

Principal Investigators

  • Supriya Joshi

  • David Gewirtz

Medical Centers

  • Virginia Commonwealth University, Mineral, VA

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Mammary carcinoma

  • Breast cancer

  • Solid malignancies

Biomarkers

  • 1A/1B-light chain 3

  • Aldo-Keto Reductase Family 1 Member B

  • Annexin V

  • Autophagy-related gene 5

  • High Mobility Group Box 1

  • Sequestosome-1

  • Thioredoxin

Drug/Treatment

  • chloroquine

  • Adriamycin injection

  • Sulfasalazine

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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