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3383 : Tumor vasculature normalization by recoupling nitric oxide synthase with a tetrahydrobiopterin precursor

Researchers

Presenter

  • Christopher Rabender

Principal Investigators

  • Ninu Bruno

  • Ross B. Mikkelsen

Medical Centers

  • Virginia Commonwealth University, Mineral, VA

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Breast cancer

  • Solid malignancies

Biomarkers

  • Cluster of Differentiation 31

  • Endothelial cell nitric oxide synthase

  • Tetrahydrobiopterin

Drug/Treatment

  • Sapropterin

  • Nitric oxide

  • folitixorin calcium

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A