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3355 : Opening up heterochromatin by histone deacetylase inhibition improves response to DNA damage in lung cancer tumor initiating cells

Researchers

Presenter

  • Lovisa Lundholm

Principal Investigators

  • Petra Haag

  • Mina Eriksson

  • Beata Brzozowska

  • Rolf Lewensohn

  • Andrzej Wojcik

  • Kristina Viktorsson

Medical Centers

  • Stockholm University, Stockholm, Sweden

  • Karolinska Institutet, Stockholm, Sweden

Locations

  • Sweden

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Non Small Cell Lung cancer

  • Ataxia telangiectasia

  • Lung Cancer

  • Solid malignancies

  • Seizures sensorineural deafness ataxia mental retardation electrolyte imbalance

  • Small cell lung cancer

Biomarkers

  • DNA methylation

  • Ataxia-telangiectasia mutated

Drug/Treatment

  • trichostatin A

  • Panobinostat

  • Vorinostat

  • Cisplatin

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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