// App-Quantinova.ai

3334 : KLF4 promotes self-renewal by repressing DYRK2-mediated degradation of c-Myc in leukemic stem cells: development of targeted therapy

Researchers

Presenter

  • Chun Shik Park

Principal Investigators

  • Ye Shen

  • Koramit Suppipat

  • Julie Tomolonis

  • Monica Puppi

  • Toni-Ann Mistretta

  • Leyuan Ma

  • Michael Green

  • Daniel Lacorazza

Medical Centers

  • Baylor College of Medicine, Houston, TX

  • University of Massachusetts, Massachusetts, MA

  • University of Massachusetts, Worcester, Worcester, MA

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Chronic Myelogenous Leukemia

  • Hematology-oncology disease

  • Solid malignancies

Biomarkers

  • Breakpoint Cluster Region

  • p53

  • cMYC

  • Kruppel-like factor 4

Drug/Treatment

  • L-Tyrosine

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

Copyright © 2026. QuantiNova All rights reserved