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3086 : Cyclopamine tartrate, an anti-cancer agent targeting Hedgehog signaling, strongly interferes with mitochondrial function and suppresses aerobic respiration

Researchers

Presenter

  • Md Maksudul Alam

Principal Investigators

  • Sagar Sohoni

  • Sarada Preeta Kalainayakan

  • Massoud Garrossian

  • Li Zhang

Medical Centers

  • University of Texas at Dallas, Richardson, TX

  • Logan Natural Products, Plano, TX.

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Urology

Disease

  • Non Small Cell Lung cancer

  • Gastric Cancer

  • Small cell lung cancer

  • Basal cell carcinoma

  • Medulloblastoma

  • Prostate cancer

  • Gynaecological cancer

  • Lung Cancer

  • Solid malignancies

Biomarkers

  • Proto-oncogene tyrosine-protein kinase ROS

  • Utrophin

Drug/Treatment

  • Glutamine

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A