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3023 : Cytoplasmic sequestration and autophagic degradation of ErbB receptors in HER2-driven cancer cells by small molecule Sigma1 modulators

Researchers

Presenter

  • Christina M. Maher

Principal Investigators

  • Jane Y. Tong

  • Charles G. Longen

  • Mercedes I. Lioni

  • Jeffrey D. Thomas

  • Xing Tan

  • Logan Tyler

  • Fernando U. Garcia

  • Felix J. Kim

Medical Centers

  • Drexel Univ Coll of Medcn, Philadelphia, PA

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Breast cancer

  • Solid malignancies

Biomarkers

  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

  • Epidermal growth factor

  • Epidermal growth factor receptor

  • Erb-B2 Receptor Tyrosine Kinase 3

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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