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2981 : DNA damaging agent-induced apoptosis is controled by MCL-1 phosphorylation and degradation mediated by the Noxa/MCL-1/CDK2 complex

Researchers

Presenter

  • Wataru Nakajima

Principal Investigators

  • June Y. Lee

  • Nicolas Maxim

  • Kanika Sharma

  • Mark A. Hicks

  • Thien-Trang Vu

  • Angela Luu

  • William Andrew Yeudall

  • Nobuyuki Tanaka

  • Hisashi Harada

Medical Centers

  • Massey Cancer Center, Richmond, VA

  • Georgia Regents University, August, GA

  • Nippon Medical School, Kawasaki, Japan.

Locations

  • United States

  • Japan

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Solid malignancies

Biomarkers

  • Cyclin dependent kinase 2

Drug/Treatment

  • Etoposide

  • Etoposide phosphate

  • Cisplatin

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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