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2956 : Optimal PEGylation of an auristatin linker provides ADCs with improved pharmacological properties

Researchers

Presenter

  • Patrick J. Burke

Principal Investigators

  • Joseph Z. Hamilton

  • Scott C. Jeffrey

  • Joshua H. Hunter

  • Julia H. Cochran

  • Nagendra Chemuturi

  • Martha E. Anderson

  • Peter D. Senter

  • Robert P. Lyon

Medical Centers

  • Seattle Genetics, Bothell, WA

Locations

  • United States

Companies

  • Seattle Genetics, In

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Solid malignancies

Biomarkers

  • Apparent diffusion coefficient

Drug/Treatment

  • monomethyl auristatin E

Outcome

  • N/A

Study Design

  • Pharmacokinetics

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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