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2922 : Loss of retinoblastoma protein dysregulates HIF1-mediated genetic programs, and promotes tumor cell invasiveness and neuroendocrine differentiation in prostate cancer cells

Researchers

Presenter

  • Mark Labrecque

Principal Investigators

  • Mandeep Takhar

  • Rebecca J. Nason

  • Stephanie Santacruz

  • Kevin Tam

  • Shabnam Massah

  • Anne Haegert

  • Robert Bell

  • Manuel Altamirano-Dimas

  • Colin Collins

  • Frank Lee

  • Gratien Prefontaine

  • Michael Cox

  • Timothy Beischlag

Medical Centers

  • Simon Fraser University, Vancouver, BC, Canada

  • University of British Columbia, Vancouver, British Columbia, Canada.

  • Vancouver Prostate Ctr., Vancouver, British Columbia, Canada

Locations

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Urology

Disease

  • Prostate cancer

  • Retinoblastoma

  • Solid malignancies

Biomarkers

  • Enolase 2

  • Extracellular signal-regulated kinase

  • HIF 1 beta

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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