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2921 : The retinoblastoma protein regulates hypoxia-inducible factor-1-mediated transcriptional programs, tumor cell invasiveness, tumor growth and metastasis in human breast cancer cells

Researchers

Presenter

  • Mandeep K. Takhar

Principal Investigators

  • Mark P. Labrecque

  • Kevin J. Tam

  • Anne Haegert

  • Robert H. Bell

  • Manuel Altamirano-Dimas

  • Colin C. Collins

  • Gratien G. Prefontaine

  • Michael E. Cox

  • Kevin L. Bennewith

  • Timothy V. Beischlag

Medical Centers

  • Simon Fraser University, Vancouver, BC, Canada

  • Vancouver Prostate Ctr., Vancouver, British Columbia, Canada

  • BC Cancer Agency, Vancouver, British Columbia, Canada.

Locations

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Retinoblastoma

  • Breast cancer

  • Solid malignancies

Biomarkers

  • Mitogen-activated protein kinase 3

  • HIF 1 beta

  • Hypoxia-inducible factor-1

Drug/Treatment

  • folitixorin calcium

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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