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2750 : Mutations on the homologous recombination pathway in 13 cancer types

Researchers

Presenter

  • Joanne Xiu

Principal Investigators

  • Ryan Bender

  • Brian Abbott

  • Zoran Gatalica

  • Sandeep Reddy

  • Mohamed Salem

  • Shelly Seward

Medical Centers

  • Caris Life Sciences, Phoenix, AZ

  • Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC

  • Karmanos Cancer Institute, Detroit, MI

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Genetic Disorder

Disease

  • Gastric Cancer

  • Advanced biliary tract carcinoma

  • Glioblastoma

  • Solid malignancies

  • Fanconi anemia, complementation group A

  • ATRX syndrome

Biomarkers

  • Alpha thalassemia mental retardation X-linked protein

  • Nibrin

  • BLM helicase

  • BRCA1 associated RING domain 1

  • Breast cancer type 1 susceptibility protein

  • Breast cancer type 2 susceptibility protein

  • Phosphatase and tensin homolog

  • Checkpoint kinase 1

  • checkpoint kinase 2

  • RAD51 Recombinase

  • Excision repair cross-complementation group 1

  • Fanconi anaemia, complementation group A

  • Partner and localizer of BRCA2

  • BRCA1 interacting protein

  • Ataxia-telangiectasia mutated

Drug/Treatment

  • Oxaliplatin, 5-fluorouracil and folic acid

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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