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2626 : Metabolic profiles and potential pharmacodynamic biomarkers in female Sprague-Dawley rats on a standard (4% fat) or Western (20% fat) diet and treated with known active or inactive chemopreventive agents

Researchers

Presenter

  • Matthew D. Thompson

Principal Investigators

  • Clinton J. Grubbs

  • Vernon E. Steele

  • Mark S. Miller

  • Fariba Moeinpour

  • Edward D. Karoly

  • Ronald A. Lubet

Medical Centers

  • National Cancer Institute, Bethesda, MD

  • University of Alabama at Birmingham, Birmingham, AL

  • Metabolon, Triangle Park, NC.

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Solid malignancies

Biomarkers

  • N/A

Drug/Treatment

  • Metformin controlled release

  • Nicotinamide

  • Bexarotene

  • Carnitine

  • Metformin Hydrochloride

  • Tamoxifen

  • NaBen

  • Atorvastatin

  • Iressa Oral

Outcome

  • N/A

Study Design

  • Pharmacodynamics

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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