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2618 : Oncogenic mutant KRAS modulates CREB activation through MEK-ERK and AKT signaling in pancreatic cancer

Researchers

Presenter

  • Jason Castellanos

Principal Investigators

  • Supriya Srinivasan

  • Kumar Honnenahally

  • Chanjuan Shi

  • Michael Van Saun

  • David Robbins

  • Nipun Merchant

  • Nagaraj Nagathihalli

Medical Centers

  • Department of Biochemistry, Vanderbilt University, Nashville, TN

  • University of Miami Miller School of Medicine, Sylvester Comprehensive Cancer Center, Miami, FL

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Pancreas ductal adenocarcinoma

  • Pancreatic cancer

  • Solid malignancies

  • Microphthalmia, syndromic, 9

Biomarkers

  • CREB-binding protein

  • Cyclic adenosine monophosphate

  • KRAS proto-oncogene, GTPase

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Final

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