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2497 : ONC201 targets cancer stem cells in colorectal, prostate and glioblastoma multiforme tumors via modulation of stem cell-related gene expression

Researchers

Presenter

  • Varun Vijay Prabhu

Principal Investigators

  • Joshua E. Allen

  • Dan Zhao

  • Amriti R. Lulla

  • Christina Leah B. Kline

  • A. Pieter J. van den Heuvel

  • Avital Lev

  • Tracy T. Batchelor

  • David T. Dicker

  • Andrew S. Chi

  • Wafik S. El-Deiry

Medical Centers

  • Fox Chase Cancer Center, Philadelphia, PA

  • Oncoceutics, Philadelphia, PA

  • Massachusetts General Hospital Cancer Center and Harvard Medical School, Boston, MA

  • Penn State Hershey Cancer Institute, Department of Medicine (Hematology/Oncology), Penn State College of Medicine, Hershey, PA.

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Urology

Disease

  • Hematological malignancies

  • Glioblastoma

  • Solid malignancies

  • Prostate cancer

  • Colorectal Cancer

  • Gliomas

Biomarkers

  • Cluster of Differentiation 44

  • Wnt Family Member 16

Drug/Treatment

  • TIC 10

Outcome

  • N/A


Study Design

  • N/A

Phase

  • I/II

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A