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2482 : The Calcineurin/NFAT pathway mediates tumor initiating cell and drug resistance in lung cancer through SOX2 enhancer binding and ALDH upregulation

Researchers

Presenter

  • Zhi-Jie Xiao

Principal Investigators

  • Jing Liu

  • Vicky PC Tin

  • Maria P. Wong

Medical Centers

  • The Chinese University of Hong Kong, Hong Kong, Hong Kong

Locations

  • Hong Kong

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Lung Cancer

  • Solid malignancies

Biomarkers

  • Proto-oncogene tyrosine-protein kinase ROS

  • SRY-Box 2

Drug/Treatment

  • N-acetylcysteine

  • gefitinib

  • Cisplatin

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A