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2476 : DiSCoVERing innovative therapies for rare tumors: Combining genetically accurate disease models with advanced in silico analysis to identify novel therapeutic targets

Researchers

Presenter

  • Allison Rose Hanaford

Principal Investigators

  • Antoinette Price

  • Ulf Kahlert

  • Jarek Maciaczyk

  • Nikkhah Guido

  • Wlliam Kim

  • Tobias Ehrenberger

  • Paul Clemons

  • Vlado Dancik

  • Brinton Seashore-Ludlow

  • Vasanthi Viswanathan

  • Michelle Stewart

  • Matthew Rees

  • Alykahn Shamji

  • William Hahn

  • Stuart Schreiber

  • Ernest Fraenkel

  • Scott Pomeroy

  • Jill Mesirov

  • Pablo Tamayo

  • Charles G. Eberhart

  • Eric H. Raabe

Medical Centers

  • Johns Hopkins University School of Medicine, Baltimore, MD

  • Boston Children's Hospital, Boston, MA

  • University Medical Center Dusseldorf, Dusseldorf, Germany

  • Universitatsklinikum Freiburg, Freiburg, Germany

  • Broad Institute of MIT and Harvard, Cambridge, MA

  • FMI, Cambridge, MA

  • Karolinska Institutet, Stockholm, Sweden

  • University of California-San Diego, San Diego, CA

Locations

  • United States

  • Germany

  • Sweden

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Medulloblastoma

  • Brain cancer

  • Solid malignancies

Biomarkers

  • p53

  • Cyclin-dependent kinase 4

  • Telomerase reverse transcriptase

Drug/Treatment

  • Palbociclib

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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