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2474 : DFMO targets cancer stem cells in neuroblastoma

Researchers

Presenter

  • Tracey Avequin

Principal Investigators

  • Ping Zhao

  • Abhinav Nagulapally

  • Jeffrey Bond

  • Ebrahim Azizi

  • Max Wicha

  • Giselle L. Saulnier Sholler

Medical Centers

  • Helen DeVos Children's Hospital, Grand Rapids, MI.

  • University of Vermont, Grand Rapids, MI

  • University of Michigan, Grand Rapids, MI

  • University of Michigan, Ann Arbor, MI

  • Helen DeVos Children's Hospital and Michigan State University, Grand Rapids, MI.

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Neuroblastoma

  • Solid malignancies

Biomarkers

  • MYCN proto-oncogene, bHLH transcription factor

  • NANOG

  • C-X-C motif chemokine receptor 4

  • Kruppel-like factor 4

  • SRY-Box 2

Drug/Treatment

  • Ribo-100

  • Eflornithine

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Final

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