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2446 : Ezrin inhibition up-regulates stress response gene expression and blocks osteosarcoma metastasis

Researchers

Presenter

  • Haydar Celik

Principal Investigators

  • Gulay Bulut

  • Jenny Han

  • Garrett T. Graham

  • Tsion Z. Minas

  • Erin J. Conn

  • Sung-Hyeok Hong

  • Gary T. Pauly

  • Mutlu Hayran

  • Xin Li

  • Metin Ozdemirli

  • Ayse Ayhan

  • Michelle A. Rudek

  • Jeffrey A. Toretsky

  • Aykut Uren

Medical Centers

  • Department of Pathology, Georgetown University Medical Center, Washington, DC

  • Department of Molecular Biology and Genetics, Faculty of Engineering and Natural Sciences, Bahcesehir University, Istanbul, Turkey

  • Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, MD

  • Department of Preventive Oncology, Cancer Institute, Hacettepe University, Ankara, Turkey

  • Department of Biostatistics, Bioinformatics, and Biomathematics, Georgetown University, Washington, DC

  • Department of Pathology, Georgetown University Medical Center, Washington, DC

  • Department of Pathology, Seirei Mikatahara Hospital and Hamamatsu University School of Medicine, Hamamatsu, Japan

  • The Johns Hopkins University School of Medicine, Department of Oncology and Department of Medicine, Division of Clinical Pharmacology and The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD.

Locations

  • United States

  • Turkey

  • Japan

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Rhabdomyosarcoma

  • Osteosarcoma

  • Solid malignancies

  • Malaria

Biomarkers

  • N/A

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • Pharmacokinetics

  • Pharmacodynamics

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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