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2353 : Combination immunotherapy: T-cell costimulation (OX40L, TL1A, 4-1BBL and ICOSL) secreted locally by Gp96-Ig vaccines, elicits robust antigen-specific, memory T cell responses and tumor elimination

Researchers

Presenter

  • George J. Fromm

Principal Investigators

  • Suresh de Silva

  • Louise Giffin

  • Jason Rose

  • Aditi Goyal

  • Taylor H. Schreiber

Medical Centers

  • Heat Biologics, Durham, NC

Locations

  • United States

Companies

  • Heat Biologics, Inc.

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Solid malignancies

Biomarkers

  • Cluster of Differentiation 4

  • Cluster of differentiation 8A

  • Forkhead Box P3

  • Interleukin-2

  • TNF receptor superfamily member 25

  • Tumor necrosis factor

  • Regulatory T cells

Drug/Treatment

  • OX40L

  • GP96

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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