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2332 : Patient-derived tumor xenografts in humanized NSG-SGM3 mice: a new immuno-oncology platform

Researchers

Presenter

  • Li-Chin Yao

Principal Investigators

  • Mingshan Cheng

  • Minan Wang

  • Jacques Banchereau

  • Karolina Palucka

  • Leonard Shultz

  • Carol Bult

  • James G. Keck

Medical Centers

  • The Jackson Laboratory, Sacramento, CA

  • The Jackson Laboratory, Sacramento, CA

  • The Jackson Laboratory, Bar Harbor, ME

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Solid malignancies

Biomarkers

  • Cluster of Differentiation 34

  • Cluster of differentiation 45

  • Granulocyte-macrophage-colony stimulating factor

  • Regulatory T cells

Drug/Treatment

  • Pembrolizumab

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A