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2281 : DNA methyl transferase inhibitors (DNMTis) upregulate NY-ESO expression in several human primary cells: implications for co-therapy with engineered adoptive T-cell therapies

Researchers

Presenter

  • Bruno Laugel

Principal Investigators

  • Alexandra Sevko

  • Karen Howe

  • Zoltan Ferjentsik

  • Tiago Ferronha

  • Miguel Maroto

  • Joanna Brewer

  • Bent Jakobsen

  • Gwendolyn Binder-Scholl

Medical Centers

  • Adaptimmune Ltd, Oxfordshire, United Kingdom

  • Adaptimmune, Philadelphia, PA

Locations

  • United States

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Hematological malignancies

  • Solid malignancies

Biomarkers

  • N/A

Drug/Treatment

  • Decitabine

  • 5-Azacytidine

  • Vidaza

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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