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2228 : Cbl-b inhibitors as novel intra-cellular checkpoint inhibitors for cancer immunotherapy

Researchers

Presenter

  • Saket Agarwal

Principal Investigators

  • Jian Wu

  • Chris Riling

  • Matthew Kodrasov

  • Joseph Weinstock

  • Ivan Sokirniy

  • Michael Mattern

  • Taku Kambayashi

  • Suresh Kumar

Medical Centers

  • Progenra Inc, Malvern, PA

  • University of Pennsylvania, PA.

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Solid malignancies

  • Lymphomas

Biomarkers

  • Natural Killer cells

  • Cluster of differentiation 8A

  • E3 ubiquitin-protein ligase CBL

  • Interleukin-2

  • Stromal interaction molecule 1

Drug/Treatment

  • Anti-CTLA4

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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