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2212 : Induction of 51 integrin expression rescues geriatric CAR-T cell function

Researchers

Presenter

  • Prajna Guha

Principal Investigators

  • Marissa Cunetta

  • Ponnandai Somasundar

  • N J. Espat

  • Richard P. Junghans

  • Steven C. Katz

Medical Centers

  • Roger Williams Med Center, Providence, RI

  • Tufts Medical Center, Boston, MA

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Solid malignancies

Biomarkers

  • Carcinoembryonic antigen

  • Phosphorylated signal transducer and activator of transcription 3

  • Phosphorylated signal transducer and activator of transcription 5

  • Phosphorylated-AKT

  • Phosphorylated-extracellular signal regulated kinase

  • Cluster of Differentiation 4

  • Cluster of differentiation 8A

  • Colony stimulating factor 1

  • Interleukin-15

  • Interleukin-2

Drug/Treatment

  • N/A

Outcome

  • N/A


Study Design

  • N/A

Phase

  • I

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A