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2122 : Downregulation of RGS10 induces PI3K/mTOR inhibitor resistance by Ras activation in glioblastoma

Researchers

Presenter

  • Xiaolong Li

Principal Investigators

  • Shaofang Wu

  • Dimpy Koul

  • W.K. Alfred Yung

Medical Centers

  • 1.MD Anderson Cancer Center, Houston, TX

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Glioblastoma

  • Brain cancer

  • Solid malignancies

Biomarkers

  • Mitogen-activated protein kinase 3

  • p70S6 kinase

  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

  • Extracellular signal-regulated kinase

  • Serine/threonine-protein kinase mTOR

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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