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2119 : Acquired nintedanib resistance in FGFR1-driven small cell but not non-small cell lung cancer is mediated by ABCB1

Researchers

Presenter

  • Bernhard Englinger

Principal Investigators

  • Daniela Lotsch

  • Christine Pirker

  • Sushilla van Schoonhoven

  • Bernd Boidol

  • Charles Lardeau

  • Stefan Kubicek

  • Pal Szabo

  • Gergely Szakacs

  • Walter Berger

Medical Centers

  • Institute of Cancer Research, Vienna, Austria

  • Research Center for Molecular Medicine, Vienna, Austria

  • Institute of Organic Chemistry, Hungarian Academy of Sciences, Budapest, Hungary

  • Institute of Enzymology, Hungarian Academy of Sciences, Budapest, Hungary.

Locations

  • Austria

  • Hungary

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Non Small Cell Lung cancer

  • Lung Cancer

  • Solid malignancies

  • Small cell lung cancer

Biomarkers

  • ATP Binding Cassette Transporter B1

  • Platelet-derived growth factor receptor

  • Fibroblast growth factor receptor

  • Fibroblast growth factor receptor 1

  • Kinase Insert Domain Receptor

Drug/Treatment

  • Nintedanib

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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