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1885 : Integrated epigenomic profiling reveals widespread demethylation in melanoma and points to the role of CSF1R-RUNX1 axis in resistance against BRAF inhibition

Researchers

Presenter

  • Orsolya Giricz

Principal Investigators

  • Caroline H. Hu

  • Kimberly Dahlman

  • Nandini Ramachandra

  • Matthias Bartenstein

  • Kith Pradhan

  • Tushar Bhagat

  • Yiting Yu

  • Hoa Nguyen

  • Elizabeth Burton

  • Bernice Matusow

  • Gaston Habets

  • Rafe Shellooe

  • Gideon Bollag

  • Brian West

  • John Greally

  • Jeffrey Sosman

  • Paraic Kenny

  • Amit Verma

Medical Centers

  • Albert Einstein College of Medicine, Great Neck, NY

  • Vanderbilt University Medical Center, Nashville, TN

  • Plexxikon Inc, Berkeley, CA

Locations

  • United States

Companies

  • Plexxikon Inc.

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Melanoma

  • Solid malignancies

Biomarkers

  • B-Raf proto-oncogene, serine/threonine kinase

  • DNA methylation

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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