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1729 : Withaferin A blocks formation of IFN-induced metastatic cancer stem cells through inhibition of the CXCR4/CXCL12 pathway in the UP-LN1 carcinoma cell model

Researchers

Presenter

  • Andy Shau-Bin Chou

Principal Investigators

  • Li-Lei Ting

  • Chin-Hsuan Hsieh

  • See-Tong Pang

  • Shuen-Kuei Liao

Medical Centers

  • Buddhist Tzu Chi General Hospital, Hualien, Taiwan.

  • Taipei Medical University, Taipei, Taiwan

  • Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan

Locations

  • Taiwan

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Gastrointestinal stromal tumor

  • Solid malignancies

  • Gastric Cancer

Biomarkers

  • Immunoglobulin G

  • Interleukin 6

  • Signal transducer and activator of transcription 3

  • Stromal cell-derived factor 1

Drug/Treatment

  • CXCL12

  • IFN-lambda

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A