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1489 : Development of a humanized ROR1 x CD3 bispecific DART molecule for the treatment of solid and liquid tumors

Researchers

Presenter

  • Bhaswati Barat

Principal Investigators

  • Gurunadh Chichili

  • Valentina Ciccarone

  • James Tamura

  • Sergey Gorlatov

  • Michael Spliedt

  • Francine Chen

  • Scott Koenig

  • Paul Moore

  • Ezio Bonvini

  • Ralph Alderson

  • Syd Johnson

Medical Centers

  • MacroGenics, Inc., Rockville, MD

  • MacroGenics, Inc, South San Francisco, CA

Locations

  • United States

Companies

  • MacroGenics, Inc.

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Mantle cell lymphoma

  • Lung Cancer

  • Solid malignancies

  • Lymphomas

Biomarkers

  • Cluster of Differentiation 2AP

  • DNA Damage Inducible Transcript 3

  • Interleukin-2

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • Pharmacokinetics

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Final

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