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1475 : Local immune activation resulting in tumor growth inhibition with MEDI9197 - an intratumorally administered TLR7/8 agonist

Researchers

Presenter

  • Stefanie Mullins

Principal Investigators

  • Iwen Grigsby

  • Lester I. Harrison

  • Song Ren

  • Serguei Soukharev

  • Lesley Young

  • James M. Elvecrog

  • Robert W. Wilkinson

  • Mark A. Tomai

  • Ronald Herbst

  • John P. Vasilakos

  • Andrew J. Leishman

Medical Centers

  • MedImmune, Cambridge, United Kingdom

  • M, St. Paul, MN

  • MedImmune, Gaithersburg, MD

Locations

  • United States

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Solid malignancies

Biomarkers

  • Cluster of differentiation 69

  • Cluster of differentiation 8A

  • Interleukin 12

  • tumor-infiltrating lymphocytes

Drug/Treatment

  • Interferon alpha

  • Interleukin

  • Interferon

  • IL-12

  • IFN-lambda

Outcome

  • N/A

Study Design

  • Pharmacokinetics

  • Adaptive

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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