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1456 : Dexamethasone suppresses cytokine-induced dual oxidase 2 (Duox2) and VEGF-A expression in human pancreatic cancer cells in vitro and pancreatic cancer growth in xenografts

Researchers

Presenter

  • Yongzhong Wu

Principal Investigators

  • Smitha Antony

  • Jennifer L. Meitzler

  • Jiamo Lu

  • Agnes Juhasz

  • Guojian Jiang

  • Krishnendu Roy

  • James H. Doroshow

Medical Centers

  • NIH-NIDCD, Bethesda, MD.

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Genetic Disorder

Disease

  • Pancreas ductal adenocarcinoma

  • Pancreatitis

  • Hereditary pancreatitis

  • Pancreatic cancer

  • Solid malignancies

  • Microphthalmia, syndromic, 9

  • Pancreatic and cerebellar agenesis

Biomarkers

  • Proto-oncogene tyrosine-protein kinase ROS

  • Interleukin 17A

  • Interleukin 4

  • Vascular endothelial growth factor A

Drug/Treatment

  • Glucocorticoid

  • Dexamethasone

  • Dekpak 13 Day Taperpak

  • Mifepristone

  • IL-4

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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