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1413 : Treatment of mouse liver and brain colon cancer metastases with Toca 511 and 5-fluorocytosine for intratumoral production of 5-fluorouracil leads to increased survival, induction of antitumor immune responses, and reduction of MDSC

Researchers

Presenter

  • Maria Rodriguez-Aguirre

Principal Investigators

  • Kader Yagiz

  • Fernando Lopez Espinoza

  • Daniel Mendoza

  • Tiffany T. Huang

  • Carlos Ibanez

  • Harry E. Gruber

  • Douglas J. Jolly

  • Joan Robbins

Medical Centers

  • Tocagen, San Diego, CA.

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Gastroenterology (GU)

Disease

  • Colorectal Cancer

  • Brain metastasis

  • Solid malignancies

Biomarkers

  • N/A

Drug/Treatment

  • Adrucil injection

  • vocimagene amiretrorepvec + Toca FC

Outcome

  • N/A

Study Design

  • N/A

Phase

  • I

Study Id's

  • NCT02414165

Sponsors

  • N/A

Result

  • N/A

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