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1228 : Indolo-pyrido-isoquinolin based alkaloid inhibits epithelial-mesenchymal transition and stemness via activation of p53-miR34a axis

Researchers

Presenter

  • Arumugam Nagalingam

Principal Investigators

  • Dimiter. B Avtanski

  • Joesph Tomaszewski

  • Risbood Prabhakar

  • Michael Difillippantonio

  • Brian Mears

  • Neeraj Saxena

  • Sanjay Malhotra

  • Dipali Sharma

Medical Centers

  • Johns Hopkins University, Baltimore, MD

  • National Institutes of Health, Baltimore, WA

  • National Institutes of Health (NIH), MD

  • National Institutes of Health (NIH), MD

  • University of Maryland, Baltimore, MD

  • National Institute of Health, Bethesda, MD

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Solid malignancies

Biomarkers

  • Solute Carrier Family 22 Member 3

  • Tumor necrosis factor

Drug/Treatment

  • N/A

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A