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1222 : Fluorinated N, N-diarylureas treatment as effective strategy to target colorectal cancer stem cells

Researchers

Presenter

  • Piotr Rychahou

Principal Investigators

  • Dasha Kenlan

  • Vitaliy M. Sviripa

  • David S. Watt

  • B. Mark Evers

Medical Centers

  • University of Kentucky Markey Cancer Center and Department of Surgery, Lexington, KY

  • University of Kentucky Markey Cancer Center, Lexington, KY

  • University of Kentucky Markey Cancer Center and Department of Molecular and Cellular Biochemistry, Lexington, KY

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Colorectal Cancer

  • Advanced refractory tumors

  • Solid malignancies

Biomarkers

  • AMP-activated protein kinase

  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

Drug/Treatment

  • Metformin Hydrochloride

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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