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1050 : Inhibition of the polyamine synthesis pathway is synthetically lethal with loss of argininosuccinate synthase 1 in cancer

Researchers

Presenter

  • Peter W. Szlosarek

Principal Investigators

  • Matthew Locke

  • Essam Ghazaly

  • Laura Lattanzio

  • Cristiana Lo Nigro

  • Sarah A. Martin

Medical Centers

  • Barts Cancer Institute & St.Bartholomew's Hospital, London, United Kingdom

  • Bart's Cancer Institute, London, United Kingdom

  • AO S. Croce e Carle, Cuneo, Italy.

Locations

  • United Kingdom

  • Italy

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Mesothelioma

  • Solid malignancies

Biomarkers

  • N/A

Drug/Treatment

  • ADI-PEG20

  • Arginine hydrochloride

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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