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851 : Analysis of cancer-initiating mosaic mutation in germline samples of pediatric cancer patients by next generation sequencing

Researchers

Presenter

  • Xiaotu Ma

Principal Investigators

  • Donald Yergeau

  • Bhavin Vadodaria

  • Joy Nakitandwe

  • John Easton

  • Sheila Shurtleff

  • Jinghui Zhang

Medical Centers

  • St. Jude Children's Research Hospital, Memphis, TN

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Retinoblastoma

  • Osteosarcoma

  • Solid malignancies

Biomarkers

  • AKT Serine

  • Retinoblastoma protein

  • Isocitrate dehydrogenase 1

  • Transcription factor Maf

  • Tumor protein p53

  • Mutant allele fractions

Drug/Treatment

  • TP53

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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