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842 : The NALP3 inflammasome and IL-1a signaling link asbestos-induced inflammation with the development of malignant mesothelioma

Researchers

Presenter

  • Yuwaraj Kadariya

Principal Investigators

  • Craig W. Menges

  • Jacqueline Talarchek

  • Qi Cai

  • Andres J. Klein-Szanto

  • Ralph A. Pietrofesa

  • Melpo Christofidou-Solomidou

  • Brooke T. Mossman

  • Arti Shukla

  • Joseph R. Testa

Medical Centers

  • Fox Chase Cancer Center, Philadelphia, PA

  • University of Pennsylvania Perelman School of Medicine, Philadelphia, PA

  • University of Vermont College of Medicine, South Burlington, VT

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Mesothelioma

  • Solid malignancies

Biomarkers

  • NLR family pyrin domain containing 3

Drug/Treatment

  • Anakinra

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A