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780 : Multi-omic profiling of gliomas reveals distinct DNA methylation changes at tumor recurrence

Researchers

Presenter

  • Lindsay C. Stetson

Principal Investigators

  • Camila Ferreira de Souza

  • Tathiane Maistro Malta

  • Thais Sarraf Sabedot

  • Quinn Ostrom

  • Peter Liao

  • Daniela Pretti da Cunha Tirapelli

  • Luciano Neder

  • Carlos Gilberto Carlotti

  • Rehan Akbani

  • Sofie Salama

  • Laila Poisson

  • Daniel Brat

  • Houtan Noushmehr

  • Jill Barnholtz-Sloan

Medical Centers

  • Case Western Reserve University School of Medicine, Cleveland, OH

  • Ribeirao Preto Medical School, University of Sao Paulo, Sao Paulo, Brazil

  • The University of Texas MD Anderson Cancer Canter, Houston, TX

  • University of California, Santa Cruz, Santa Cruz, CA

  • Henry Ford Hospital, MI

  • Winship Cancer Institute of Emory University, Atlanta, GA

Locations

  • United States

  • Brazil

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Glioblastoma

  • Gliomas

  • Solid malignancies

  • ATRX syndrome

  • Low-grade gliomas

Biomarkers

  • Alpha thalassemia mental retardation X-linked protein

  • Mitogen-activated protein kinase

  • Nucleoside diphosphate kinase A

  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

  • Solute Carrier Family 22 Member 3

  • PI3K/AKT

  • DNA methylation

Drug/Treatment

  • Tamsulosin Hydrochloride

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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