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681 : Using a genome-editing approach for the stepwise establishment of zebrafish models of pediatric high-grade gliomas and MPNSTs

Researchers

Presenter

  • Felix Oppel

Principal Investigators

  • Shuning He

  • Ting Tao

  • Mark W. Zimmerman

  • Adam D. Durbin

  • Nina Weichert

  • Dong H. Ki

  • A Thomas Look

Medical Centers

  • Dana-Farber Cancer Institute, Boston, MA

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Genetic Disorder

Disease

  • Malignant peripheral nerve sheath tumor

  • High-Grade Gliomas

  • Brain cancer

  • Gliomas

  • Solid malignancies

  • ATRX syndrome

Biomarkers

  • Alpha thalassemia mental retardation X-linked protein

  • Tumor protein p53

  • Neurofibromatosis type 1

Drug/Treatment

  • TP53

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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