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557 : Taking the sweet out of Th17 cells to potentiate immuno-oncology drugs

Researchers

Presenter

  • Sucheta Telang

Principal Investigators

  • Kavitha Yaddanadupi

  • Gilles Tapolsky

  • Rebecca Redman

  • Jason Chesney

Medical Centers

  • The University of Louisville, Louisville, KY

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Genetic Disorder

  • Endocrine/metabolic Diseases (ME)

Disease

  • Melanoma

  • Solid malignancies

  • Propionic acidemia

Biomarkers

  • Cluster of Differentiation 4

  • Cluster of differentiation 8A

  • Hypoxia-inducible factor-1

  • Interleukin 17A

  • 6-Phosphofructo-2-Kinase

Drug/Treatment

  • Imlygic

  • Anti-CTLA4

  • PFK158

  • GM-CSF

Outcome

  • N/A

Study Design

  • Adaptive

  • Multicenteric

Phase

  • I/II

Study Id's

  • NCT02044861

Sponsors

  • N/A

Result

  • N/A

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