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549 : Immune profiling uncovers neo-antigens and TCR repertoire responding to WX-mPD-1 and WX-mPD-L1 immune checkpoint inhibitors in syngeneic mouse xenograft models

Researchers

Presenter

  • Hua Dong

Principal Investigators

  • Yan Lu

  • Qiyao Zhang

  • Lingling Zhang

  • Xiaoyue Chen

  • Guizhu Yang

  • Shuqun Yang

  • Miao He

  • Xuzhen Tang

  • Yuxin Qin

  • Yong Zheng

  • Jiexing Cai

  • Yong Cang

  • Shaoyu Yan

  • Jing Li

  • Qunsheng Ji

Medical Centers

  • Oncology BU, WuXi AppTec, Shanghai, China

  • WuXi Biologics, Shanghai, China.

Locations

  • China

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Melanoma

  • Solid malignancies

Biomarkers

  • tumor-infiltrating lymphocytes

  • T-cell receptor

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Final

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