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432 : Loss of MGMT promoter methylation and resistance to cisplatin in non-seminomatous germ cell tumors

Researchers

Presenter

  • Catia Moutinho

Principal Investigators

  • Xavier Garcia-del-Muro

  • Elisabet Guino

  • August Vidal

  • Sara Puertas

  • Clara Munoz

  • Josep Piulats

  • Alberto Villanueva

  • Manel Esteller

Medical Centers

  • Inst. dInvestigacio Biomedica de Bellvitge (IDIBELL), Barcelona, Spain

  • Catalan Institute of Oncology, IDIBELL, Barcelona, Spain

Locations

  • Spain

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Germ cell tumor

  • Solid malignancies

Biomarkers

  • O-6-methylguanine DNA methyltransferase

Drug/Treatment

  • O6-benzylguanine

  • Temozolomide

  • Cisplatin

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A