// App-Quantinova.ai

270 : Synergistic effect with APR-246 and standard chemotherapy in small cell lung cancer cells carrying smoking-associated TP53 mutations

Researchers

Presenter

  • Nina Mohell

Principal Investigators

  • Asa Fransson

  • Jessica Alfredsson

  • Mikael von Euler

  • Ulf Bjorklund

  • Lars Abrahmsen

Medical Centers

  • Aprea AB, Solna, Sweden

Locations

  • Sweden

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Hematological malignancies

  • Small cell lung cancer

  • Gynaecological cancer

  • Lung Cancer

  • Solid malignancies

Biomarkers

  • p53

Drug/Treatment

  • Carboplatin

  • Etoposide

  • Etoposide phosphate

  • Cisplatin

  • APR-246

  • TP53

Outcome

  • N/A

Study Design

  • First-In-Human

Phase

  • I

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Final

Copyright © 2026. QuantiNova All rights reserved