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257 : Evaluation of organic cation transporter 1 (OCT1, SLC22A1) as transporter for sorafenib

Researchers

Presenter

  • Claudia Neul

Principal Investigators

  • Sharyn D. Baker

  • Alex Sparreboom

  • Elke Schaeffeler

  • Stefan Laufer

  • Matthias Schwab

  • Anne T. Nies

Medical Centers

  • Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology and University of Tubingen, Stuttgart, Germany

  • Division of Pharmaceutics & Pharmaceutical Chemistry, College of Pharmacy, The Ohio State University, Columbus, OH

  • Dept. of Pharmaceutical and Medicinal Chemistry, Institute of Pharmaceutical Sciences, Eberhard Karls University Tubingen, Tubingen, Germany

  • Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart and Department of Clinical Pharmacology, Institute of Experimental and Clinical Pharmacology and Toxicology, University Hospital Tuebingen, Tuebingen, Germany.

Locations

  • United States

  • Germany

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Liver cancer

  • Solid malignancies

Biomarkers

  • C-C Motif Chemokine Ligand 21

Drug/Treatment

  • Sorafenib

Outcome

  • N/A

Study Design

  • Pharmacokinetics

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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