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19 : Neurofibromatosis type 1 (NF1) status determines sensitivity of soft tissue sarcoma and melanoma cell lines to glutaminase inhibitors

Researchers

Presenter

  • Tahir N. Sheikh

Principal Investigators

  • Parag P. Patwardhan

  • Gary K. Schwartz

Medical Centers

  • Department of Medicine, Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, NY

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Genetic Disorder

  • Musculoskeletal

Disease

  • Neurofibromatosis type 1

  • Soft tissue sarcoma

  • Melanoma

  • Sarcoma

  • Solid malignancies

  • Malignant peripheral nerve sheath tumor

  • Short stature, onychodysplasia, facial dysmorphism, and hypotrichosis

Biomarkers

  • Neurofibromatosis type 1

Drug/Treatment

  • Glutamine

  • CB-839

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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