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4 : Hyper activation of poly(ADP-ribose) polymerase 1 initiates large-scale metabolic changes in a cellular model of glioblastoma

Researchers

Presenter

  • Anna M. Wilk

Principal Investigators

  • Elise Fouquerel

  • Bobbie Johnston

  • Samuel A.J. Trammell

  • Lindsay Schambeau

  • Joel F. Andrews

  • Lewis Pannell

  • Sara J. Cooper

  • Charles Brenner

  • Robert W. Sobol

Medical Centers

  • Mitchell Cancer Institute, The University of South Alabama, Mobile, AL

  • Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA

  • HudsonAlpha Institute for Biotechnology, Huntsville, AL

  • Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA.

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Glioblastoma

  • Solid malignancies

Biomarkers

  • Hexokinase 1

Drug/Treatment

  • ribose

  • FK866

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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