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3777 : RNA profiles of circulating tumor cells and extracellular vesicles for therapy stratification of metastatic breast cancer patients

Researchers

Presenter

  • Corinna Keup

Principal Investigators

  • Siegfried Hauch

  • Linda Plappert

  • Markus Sprenger-Haussels

  • Pawel Mach

  • Mitra Tewes

  • Bahriye Aktas

  • Hans-Christian Kolberg

  • Rainer Kimmig

  • Sabine Kasimir-Bauer

Medical Centers

  • Department of Gynecology and Obstetrics, University Hospital Dresden, Dresden, Germany

  • QIAGEN GmbH, Hilden, Germany.

  • Department of Internal Medicine (Cancer Research), University Hospital of Essen, Essen, Germany

  • Clinic for Gynecology and Obstetrics, Marienhospital Bottrop gGmbH, Bottrop, Germany.

Locations

  • Germany

Companies

  • QIAGEN GmbH

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • N/A

Biomarkers

  • AKT Serine/Threonine Kinase 2

  • Anaplastic lymphoma Kinase

  • Neurogenic locus notch homolog protein 1

  • Aurora kinase A

  • Breast cancer type 1 susceptibility protein

  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

  • Circulating tumor cells

  • Poly(ADP-Ribose) Polymerase 1

  • Cluster of differentiation 45

  • Cytokeratin 5

  • Epidermal growth factor receptor

  • Epithelial Cell Adhesion Molecule

  • erb-b2 receptor tyrosine kinase 2

  • Erb-B2 Receptor Tyrosine Kinase 3

  • Excision repair cross-complementation group 1

  • Serine/threonine-protein kinase mTOR

Drug/Treatment

  • N/A

Outcome

  • Unknown

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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