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P3-06-02 : ONC201 kills breast cancer cells by inhibiting mitochondrial respiration

Researchers

Presenter

  • YE Greer

Principal Investigators

  • SF Gilbert

  • C Islam

  • Y Ji

  • L Gattinoni

  • C Stuelten

  • D Voeller

  • S Lipkowitz

Medical Centers

  • Laboratory of Tumor Immunology and Biology, Center for Cancer Research, National Cancer Institute, Bethesda, MD

  • Experimental Transplantation and Immunology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, United States,

  • Women's Malignancies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Breast cancer

  • Tuberculosis

  • Solid malignancies

  • Triple-negative breast cancer

Biomarkers

  • AMP-activated protein kinase

  • DNA Damage Inducible Transcript 3

  • Drought-repressed 4

  • erb-b2 receptor tyrosine kinase 2

Drug/Treatment

  • TIC 10

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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