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TPS4140 : Induction nivolumab or nivolumab/ipilimumab prior to concurrent chemoradiation plus nivolumab in patients with operable stage II/III esophageal/gastroesophageal junction cancer.

Researchers

Presenter

  • Ronan Joseph Kelly

Principal Investigators

  • Richard James Battafarano

  • K Ranh Voong

  • Stephen C. Yang

  • Eun Ji Shin

  • Chen Hu

  • Valsamo Anagnostou

  • Victor E. Velculescu

  • Josephine Louella Feliciano

  • Elizabeth Thompson

  • Kellie Nicole Smith

  • Cynthia Sears

  • Drew M. Pardoll

  • Valerie Rowe

  • Hanika Rodavia

  • Ali Imran Amjad

  • Patrizia Guerrieri

  • Blair Anderson Jobe

  • Ali Hussainy Zaidi

Medical Centers

  • The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins, Baltimore, MD

  • Department of Radiation Oncology and Molecular Radiation Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD

  • The Johns Hopkins Hospital, Baltimore, MD

  • Johns Hopkins, Baltimore, MD

  • Johns Hopkins Kimmel Comprehensive Cancer Center and Bloomberg-Kimmel Institute for Cancer Immunotherapy, Baltimore, MD

  • Johns Hopkins University School of Medicine, Baltimore, MD

  • Johns Hopkins University, Baltimore, MD

  • Johns Hopkins Kimmel Comprehensive Cancer Center and Bloomberg-Kimmel Institute for Cancer Immunotherapy, Baltimore, MD

  • University of Maryland Greenebaum Comprehensive Cancer Center (UMGCCC), Baltimore, MD

  • Department of Pathology Johns Hopkins, Baltimore, MD

  • University of Pittsburgh Medical Center, Pittsburgh, PA

  • Allegheny Health Network, Pittsburgh, PA

  • Esophageal and Lung Institute, Allegheny Health Network, Pittsburgh, PA

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • N/A

Biomarkers

  • N/A

Drug/Treatment

  • Carboplatin

  • Ipilimumab

  • Paclitaxel

  • Nivolumab

  • Bemiparin

Outcome

  • N/A


Study Design

  • Open Label

  • Single Arm

  • Multicenteric

Phase

  • III

Study Id's

  • NCT03044613

Sponsors

  • N/A

Result

  • Final